Both sides have done fairly well in the tournament, and in order to secure their berth in the finals, they will have to bring the best out of their players on Friday.
Shan Masood and Mohammad Rizwan have been the two most consistent batters in the seventh edition of the tournament so far.
Qalandars are happily placed at the second spot in the points table, while Islamabad United has struggled in the tournament.
United's captain Shadab Khan has been contributing with both bat and ball right from the start of the tournament and will be crucial again.
While the clash between Islamabad United and Karachi Kings guarantees an exciting battle between bat and ball, both teams have excellent sets of players who will give enough options to form fantasy teams.
It is expected to be a high-scoring contest with two England explosive openers (Roy and Alex Hales) in both teams.
Babar Azam has constantly scored for his team at the top and is expected to do the same against Islamabad United.
It will be interesting to see a roller coaster of a game where both teams are expected to fight hard for a win at the National Stadium, Karachi.
Both Quetta Gladiators and Islamabad United are coming from straight loss in their last games.
Both teams will look to get back to winning ways when they face each other on 3 February.
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