Osaka will now face Beatriz Haddad Maia in the second round of the Tokyo Open.
The shocking turn of events broke Osaka into tears as she admitted that she was in pain even before the match.
Osaka who has not played much this year will be playing her first tournament after the Roland Garros.
The Japanese star hasn’t played in the All England Open since 2019.
Gervonta Davis defeated Ronaldo Romero with a knockout win in the sixth round.
The 20-year-old hasn’t dropped a set in Miami and has won 17 consecutive matches from her championship run at the Qatar Open in February.
Osaka, who was playing her first match after bowing out of the Australian Open, was jeered early in the game. A spectator reportedly shouted “Naomi, you suck”, with Osaka complaining to the umpire.
Naomi Osaka, the current world No. 14, began her title defense with a 6-3, 6-3 win over Colombia's Camila Osorio in the first round of the 2022 Australian Open.
While Alexander Zverev and Ashleigh Barty won their matches in straight sets, Coco Gauff faced an unexpected defeat on Monday.
Naomi Osaka was emotional after her US Open title defence came to a remarkable end at the hands of Leylah Fernandez on Friday.
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